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Indiana ( (listen)) is a U.S. state in the Midwestern and Great Lakes regions of North America. It is the 38th-largest by area and the 17th-most populous of the 50 United States. Its capital and largest city is Indianapolis. Indiana was admitted to the United States as the 19th state on December 11, 1816. It borders Lake Michigan to the northwest, Michigan to the north, Ohio to the east, the Ohio River and Kentucky to the south and southeast, and the Wabash River and Illinois to the west. Before becoming a territory, various indigenous peoples inhabited Indiana for thousands of years.